Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands

Bioorganic & Medicinal Chemistry Letters（2009）

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摘要

Synthesis and SAR of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands are reported.

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关键词

5-HT,Serotonin,5-Hydroxytryptamine,5-HT6,5-Hydroxytryptamine-6,Alzheimer’s disease,Schizophrenia,Cognition,Cognitive impairment,Cognitive dysfunction

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