Effects of hydroxyethyl starch (130 kD) on brain inflammatory response and outcome during normotensive sepsis

Xiaomei Feng,Fujun Zhang,Rong Dong,Haibin Wang,Jian Liu,Xuesheng Liu,Weiyan Li, Jingxin Yao, Jianguo Xu,Buwei Yu

International Immunopharmacology（2010）

引用 13|浏览8

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摘要

HES could ameliorate BBB dysfunction and inflammation mediators by modulating brain TLR2 and TLR4 expression during sepsis. However, HES could not improve clinical outcome.

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关键词

Hydroxyethyl starch 130/0.4,Blood–brain barrier permeability,TNF-α,Nuclear factor-kappa B,Toll-like receptor

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