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Interactions between complement and coagulation in mouse lung hyperacute rejection: Characterization using soluble thrombin inhibition and APT070, a novel membrane-bound complement inhibitor

B NGUYEN,T ZHANG,A LAARIS, N COPPARD,B BRADFORD,R PIERSONIII,A AZIMZADEH

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2005）

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Abstract
The mechanism of hyperacute lung rejection (HALR) is not completely understood, but appears less dependent on antibody and complement than HAR of other organs. Here we investigated the interaction between complement and thrombin activation in HALR.
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Key words
mouse lung hyperacute rejection,soluble thrombin inhibition,complement,coagulation,membrane-bound
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