Immunocyto- and histochemical profiling of nucleostemin expression: marker of epidermal stem cells?
Journal of dermatological science(2006)
Abstract
Nucleostemin positivity cannot be considered as marker for stem cells in skin sections. In cultured cells, nucleostemin is expressed in a distinct population of the epidermal cells from hair follicle kept in the presence of a feeder layer, intimating an association of nucleostemin expression with this type of epithelio-mesenchymal interaction which is not essential during propagation of malignant cells.
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