Prognostic Value Of Coronary Artery Calcium Score In Stable Angina Pectoris Patients Underwent Percutaneous Coronary Intervention

Objective To evaluate whether coronary artery calcium score(CCS)is an independent prognostic factor in stable angina pectoris patients underwent percutaneous coronary intervention(PCI).Methods One hundred and nine stable angina pectoris patients underwent first PCI were enrolled and followed up.Electron-beam computed tomography(EBCT)was examined in all patients before PCI and CCS was calculated.Main adverse cardiac events(MACE)were defined as a combined end point of death,non-fatal myocardial infarction,target lesion revascularization and rehospitalization for cardiac ischemic events.Results CCS was positively correlated with age(r=0.42,P=0.000).It was higher in male patients and diabetes mellitus patients when compared with female patients and non-diabetes mellitus patients.After average 15.0 months(3-40 months)of follow-up,Kaplan-Meier survival analysis showed the patients with CCS≤300,CCS 301~1000 and CCS>1000 had significantly different cumulative non-events survival rates(88.2% vs 81.6% vs 62.5%,Log rank 7.49,P=0.024).Adjusted for other confounders,multivariate Cox regression analysis showed the risk of occurrences of MACE increased 3.44 folds in the patients with CCS>1000 compared with the patients with CCS≤300(HR=3.44,P=0.043).Conclusion CCS is an independent predictor of long-term occurrences of MACE in stable angina pectoris patients treated with PCI.