The discovery of equipotent PPARα/γ dual activators
Bioorganic & Medicinal Chemistry Letters(2008)
摘要
We report the design and synthesis of equipotent PPARα/γ dual agonists starting from the selective PPARα agonist 1. In vivo data for 7 in the Zucker fa/fa rat are presented.
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关键词
PPARα,PPARγ,Dual,Agonist
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