Drug Insight: eplerenone, a mineralocorticoid-receptor antagonist
Nature clinical practice. Endocrinology & metabolism(2008)
摘要
ldosterone has many roles beyond water and sodium homeostasis, including blood pressure regulation. It is important in development of heart failure. Aldosterone binds the mineralocorticoid receptor. Eplerenone is a very specific antagonist of this receptor, and is used to treat heart failure and hypertension. It has many other potential applications, including management of ischemic heart disease and preventing progression of nephropathy.
更多查看译文
关键词
aldosterone,cardiovascular,eplerenone,hypertension
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要