Effect of Naloxon and Anisodamine on Patients after Cardiopulmonary Resuscitation

Objective: To explore the effect of Naloxon and Anisodamine on patients after cardiopulmonary resuscitation (CPR). Methods: The patients under cardiopulmonary arrest were divided into control group (group C, n=21) and treatment group (group T, n=21) in randomly. The patients in group T were treated with Naloxone (12 mg/d) and Anisodamine 4 mg/(kg·d), those in the group C treated by routine method. The questionnaires of glasgow coma scale (GCS), neurological functional insufficiency (NFI), general quality of life inventory were compared between two groups. Results: 7 days after CPR, score of GCS in group T was higher than group C, 2 months and 3 months after CPR, score of NFI was lower than group C and scores of quality of life in physical health and cognitive function was also higher than group C,all P 0.05. Conclusion: Combining Naloxon and Anisodamine can improve neurological functional status and the quality of life after CPR efficiently.