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Interferon-λ Mediates Oral Tolerance and Inhibits Antigen-Specific, T-helper-2–Mediated Inflammation in Mouse Intestine

Shao-Heng He, Xiao Chen,Chun-Hua Song,Zhi-Qiang Liu,Lin-Fu Zhou,Wen-Jing Ma,Lei-Di Zhao,Tong-Li Li,Shang-Guo Tang,Zhou Xing,Ping-Chang Yang

Gastroenterology（2011）

Cited 38|Views19
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Abstract
Conclusions: IFN-λ is involved in development and maintenance of oral tolerance in the intestines of mice; it might be used to suppress antigen-specific Th2-cell�mediated inflammation in patients.
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Key words
Food Allergy,Immune Response,Mucosal Immunity,Treg Cells
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