Avaliação epidemiológica e laboratorial de pacientes que sofreram acidente ofídico na cidade de Miracatu (Vale do Ribeira, São Paulo)

Incidents by snakes of the genus Bothrops are responsible for around 90% ofsnakebites in Brazil, constituting a major problem in human and veterinary medicine,leading to severe bleeding, tissue injury and death. The human homeostatic systemis composed of complex interactions involving blood proteins, platelets, endothelialcells and sub-endothelial structures. The bothropic venom has many componentsthat interfere with homeostasis, in the cascade of coagulation, platelet action,consumption of fibrinogen and thromboplastin. We analyzed data of 45 patientswho were victims of snakebite incidents, attended at the Emergency of Miracatu,Vale do Ribeira, Sao Paulo. 33.3% of them had non-coagulability of the blood,33.3% thrombocytopenia, and 6.9% thrombocytosis. The epidemiological datashowed that 79% of snakebite victims were male and 80% held agricultural activityat the time of the accident, thus characterizing it as a risk factor for rural workers.