Cardiopulmonary Bypass Induces the Synthesis and Release of Matrix Metalloproteinases

Joffs C,Gunasinghe H R,Multani M M,Dorman B H,Kratz J M,Crumbley A J,Crawford F A, Spinale F G

The Annals of thoracic surgery（2001）

Cited 63|Views30

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Abstract

Background. A number of cellular and molecular events can be induced after cardiac procedures requiring cardiopulmonary bypass (CPB). The matrix metalloproteinases (MMPs) are a recently discovered family of enzymes that degrade the extracellular matrix, but expression during and after CPB is unknown.

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Key words

extracellular matrix,matrix metalloproteinase,enzyme

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