Studies on genotoxic effects of iron overload and alcohol in an animal model of hepatocarcinogenesis
Journal of Hepatology(1997)
Abstract
Background/Aims: In order to examine whether iron and alcohol act synergistically during tumor initiation in vivo, we investigated the effects of dietary iron overload and a liquid ethanol-containing diet on the initiation phase of the Solt & Farber model for chemical hepatocarcinogenesis.
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Key words
Ethanol,Genotoxicity,Hemochromatosis,Hepatocarcinogenesis,Initiation,Iron,Liver damage
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