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Studies on genotoxic effects of iron overload and alcohol in an animal model of hepatocarcinogenesis

P Stål,J Olsson,P Svoboda,R Hultcrantz,M Harms-Ringdahl,L C Eriksson

Journal of Hepatology（1997）

Cited 12|Views15
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Abstract
Background/Aims: In order to examine whether iron and alcohol act synergistically during tumor initiation in vivo, we investigated the effects of dietary iron overload and a liquid ethanol-containing diet on the initiation phase of the Solt & Farber model for chemical hepatocarcinogenesis.
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Key words
Ethanol,Genotoxicity,Hemochromatosis,Hepatocarcinogenesis,Initiation,Iron,Liver damage
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