Structure-function relationships within peripheral nerves in diabetic neuropathy: the hydration hypothesis
Diabetologia(1996)
Abstract
Summary To define the quantitative relationship between peripheral nerve structure and function imposed by endoneurial oedema in the diabetic state, we determined values for sural nerve hydration structure as measured by magnetic resonance spectroscopy, and for neurological function with scores for nerve conduction properties (NCV-score), neuropathic symptoms (NS-score), and examination signs (NE-score). The coefficient of sural nerve hydration was elevated to 30±6% (pp
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Key words
Diabetic neuropathy, magnetic resonance spectroscopy
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