Biosynthesis of Keratan Sulfate
Experimental Glycoscience(2008)
摘要
Keratan sulfate (KS) is a poly-sulfated glycosaminoglycan with a poly-N-acetyllactosamine linear chain structure. KS is a rich component in cornea, and is also present in cartilage and brain. In
cornea, KS plays important roles in maintaining water content and developing collagen matrix. Recent studies have demonstrated
its association with Alzheimer’s disease and arthritis.
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