Friedländer synthesis of the food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989)(1995)
摘要
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has been prepared in 26% yield from 3-amino-2-phenylpropenal and creatinine which were heated with N,O-bis(trimethylsilyl)acetamide at 120 degrees C for 2 h. Under certain other conditions, the main product was a pyrimidine derivative.
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关键词
2-amino-1-methyl-6-phenylimidazo45-bpyridine,friedländer synthesis,food carcinogen
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