A new alkaloid and its artificial derivative with an indazole ring from Nigella glandulifera.

A new compound, nigeglanine (1), and its new artificial derivative (la), were isolated from the seeds of Nigella glandulifera, together with a known aporphine alkaloid, fuzitine (2). Their structures were established by spectral analysis, including two-dimensional (2D)-NMR spectroscopy. Nigeglanine (1) is the third natural product determined to contain an indazole nucleus.