Persistance Of Antineutrophil Cytoplasmic Antibodies In Asymptomatic Patients With Periarteritis-Nodosa And Churg-Strauss-Syndrome - Follow-Up Of 54 Patients

ANCA have been described in association with Wegener's granulomatosis, and other systemic vasculitis. Methods to detect the ANCA are indirect immunofluorescence (IFA) and ELISA. We report a retrospective study of 54 patients with proven polyarteritis nodosa (PAN) or Churg-Strauss syndrome (CSS) and concentrate on 5 patients with persistence of ANCA after remission of the disease and establish the significance of ANCA in long term follow-up of PAN and CSS.