Anti-Tumor Necrosis Factor (Tnf) Treatment Decreases Apoptosis Of Gut Epithelial Cells: A Novel Mechanism Of Anti-Tnf Therapy In Experimental Crohn'S Disease (Cd)

cells, and in part of surface epithelium weakly.Renin and ACE were present near angiotensin II receptors.Angiotensinogen was also detected by RT-PCR.Conclusions: These findings demonstrated that angiotensin II receptors and RAS component were present in human colonic mucosa, and suggest that local RAS may exist in colonic mucosa and regulate electrolyte transport by paracrine and/or autocrine actions.