Nucleotide sequence of exons 2 and 3 of the novel HLA-Cw*12032 allele

TISSUE ANTIGENS(2001)

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摘要
A novel HLA-C nucleotide sequence was discovered in an individual of Pacific Island, Tongan ethnicity using sequencing based typing. The sequence was given an official allele designation HLA-Cw*12032 by the WHO Nomenclature Committee for Factors of the HLA System. The novel sequence has 2 bp substitutions compared to the HLA-Cw*1203 at codon 134 "T" to "C" and codon 135 "C" to "G". However, when converted to amino acid sequences HLA-Cw*1203 and HLA-Cw*12032 are identical and would not have direct clinical implications.
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关键词
HLA-C antigens,HLA-Cw*12032,Pacific Islands,Tonga
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