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林茜草根醇提取物对S-180荷瘤小鼠抗肿瘤活性试验研究

Journal of Chengdu University of Traditional Chinese Medicine(2011)

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Abstract
用林茜草根醇提取物给予S-180荷瘤小鼠连续灌胃,10 d后测定林茜草根醇提取物对荷S-180瘤小鼠抑瘤率、碳粒廓清指数、小鼠外周血-肿瘤坏死因子(TNF-α)和白介素-2(IL-2)含量的影响。结果表明,林茜草根醇提取物对荷S-180瘤小鼠肿瘤的抑瘤率达39.67%,可提高小鼠吞噬碳粒廓清的指数,血清中IL-2和TNF-α的含量同样提高显著。试验结果揭示,林茜草根醇提取物抑制S-180荷瘤小鼠的抗肿瘤机理可能同增强和提高宿主的免疫功能相关。
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Key words
carbon clearance index,tumor necrosis factor TNF-α,from Roots by Ethanol,Rubia sylvatica,IL2
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