409 DIFFERENCES IN QUANTITATIVE MR IMAGING OF CARTILAGE MORPHOLOGY BETWEEN SAGITTAL VERSUS CORONAL ACCQUISITIONS OF THE FEMOROTIBIAL JOINT

Presentationsning, 11 significant thickening, and 45 no significant change (in any medial subregion) compared with healthy knees.Only few parameters (WOMAC stiffness, JSW, knee alignment, ThC, and sCTXI) predicted significant cartilage thinning versus no thinning (= thickening or no change); a low ThC of cMF was the strongest predictor of cartilage thinning.Significant cartilage thickening versus no change was predicted by higher WOMAC function scores and a smaller standard deviation of T2.No significant differences between groups were found for age, BMI, pain, meniscus pathology and other biochemical biomarkers.Conclusions: Only few parameters predicted significant cartilage thinning, the strongest being baseline cartilage thickness in the medial femur (AUC=0.81).Participants with significant cartilage thickening (but also with significant thinning) were identified by increase WOMAC function scores and a smaller SD of T2 compared with OA knees with no change.