Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

Synthesis and Evaluation of Some 1,2,3,4-Tetrahydropyrimidine-2-thione and Condensed Pyrimidine Derivatives as Potential Antihypertensive Agents.

Magda M. F. Ismail,Nehad A. M. El-Sayed,Heba S. Rateb,Mohey Ellithey,Yousry A. Ammar

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH（2011）

Cited 4|Views2
No score
Abstract
Some new tetrahydropyrimidine-2thione, octahydroquinazoline-2-thione and thiazolo[3,2-a]pyrimidine derivatives have been synthesized and tested for their antihypertensive activity. Among them, compounds 1 and 2b can be considered more potent than the reference, nifedipine (CAS 21829-25-4), while compounds 3b and 10a are equipotent to it. In addition, compound 6 showed significant antihypertensive activity.
More
Translated text
Key words
antihypertensives,octahydroqinazoline-2-thione derivatives, antihypertensive activity, synthesis,1,2,3,4-tetrahydropyrimidine-2-thione derivatives, antihypertensive activity, synthesis,thiazolo[3,2-a]pyrimidines, antihypertensive activity, synthesis
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined