The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist.
Bioorganic & Medicinal Chemistry Letters(2010)
Abstract
The identification of novel, potent, non-steroidal/small molecule functional GR antagonist GSK1564023A PR is described. Associated structure–activity relationships and the process of optimisation of an initial HTS hit are also described.
MoreTranslated text
Key words
GR antagonist,Glucocorticoid receptor,Glucocorticoid receptor antagonist
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined