Negative immune deviation induced by lithium cation
Immunology Letters(1980)
摘要
Female CBA mice were treated with lithium chloride (5 and 10 mEq/kg), and immunized with sheep red blood cells. The plaque-forming cell response was much lower in lithium-treated mice than in control saline-treated mice. Multiple injections of lithium chloride induced profound morphological changes in the spleen and thymus. These immune changes were transient.
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