ChemInform Abstract: Studies on Pyrimidine-Annulated Heterocycles: A Short Synthesis of Novel 6,9-Disubstituted Cyclohepta[b]pyrimido[5,4-d]pyrrole-8(6H),10(9H)-diones.
Cheminform(2010)
摘要
A number of 6,9-disubstituted cyclohepta[b]pyrimido[5,4-d]pyrrole-8(6H),10(9H)-dione derivatives have been synthesized in good to moderate yields by the reaction of 6-amino-3-methyluracil derivatives with 2-chlorotropone in an enamine-alkylation process, subsequent condensation of the amino group with the carbonyl function, dehydrochlorination, and dehydration.
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关键词
cyclohepta[b]pyrimido[5,4-d]pyrrole,1-azaazulene,2-chlorotropone,6-amino-3-methyluracil,enamine-alkylation
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