From castration-induced apoptosis of prostatic epithelium to the use of apoptotic genes in the treatment of prostate cancer.

HORMONE-RELATED TUMORS: NOVEL APPROACHES TO PREVENTION AND TREATMENT(2006)

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Abstract
Current knowledge of the mechanisms regulating androgen-ablation-induced apoptosis is reviewed, and our efforts to develop a system in which genes of the apoptotic pathway are used to induce therapeutic apoptosis in experimental models of prostate cancer are described.
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Key words
apoptosis,prostate cancer,castration,epithelium,genes
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