699. Bactofection into Airway Epithelial Cells In Vitro and In Vivo Using a Genetically Modified Escherichia coli
MOLECULAR THERAPY(2006)
Abstract
Bactofection has emerged as an approach for gene therapy. Here, we assessed bactofection into airway epithelial cells in vitro and in vivo using E. coli genetically engineered to enter non-phagocytosing cells (invasive strain).
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Key words
escherichia coli,gene transfer,protein synthesis,genetic engineering,pharmacology,airway epithelium,genetically modified,cell line,gene expression
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