Organophosphorus Chemistry .1. Phosphorylation Via Very Reactive Intermediates Formed Between Organophosphonodichloridates And Dimethyl Sulfoxide

Organophosphonodichloridates react exothermically with DMSO in anhydrous solvents to give P 1 P 2 -disubstituted pyrophosphoric and pyrophosphonic acids. MeSCH 2 Cl, (MeS) 2 CH 2 , Me 2 S and Me 2 S 2 were the sulphur compounds identified as by-products of the reaction. Our findings are consistent with the assumption that the active phosphorylating agents are compounds of the P-XYZ type. A mechanism for the phosphorylation reaction is proposed.