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枳实生品和麸炒品对利血平致脾虚证大鼠胃肠激素含量的影响

林桂梅,张旭,尹丽波,侯影,杨静娴,贾天柱

Guiding Journal of Traditional Chinese Medicine and Pharmacy（2012）

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Abstract
目的:研究枳实生品和麸炒品对利血平致脾虚证大鼠胃肠激素含量的影响.方法:腹腔注射利血平造成大鼠脾虚模型,双抗体夹心酶联免疫吸附法检测血中胃肠激素含量.结果:与模型组比较,枳实生品和麸炒品组大鼠胃动素和胃泌素水平升高,而血管活性肠肽和生长抑素水平降低,与模型组比较,差异均有统计学意义(P<0.05),并且麸炒品作用强于生品(P<0.05).结论:枳实生品和麸炒品均能改善利血平致脾虚证大鼠胃肠激素水平,这可能是枳实治疗脾虚证的机制之一.
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Key words
Fructus aurantii immaturus,Motilin,Vasoactive intestinal peptide,Gastrin,Somatostatin
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