Plasma Products

Apheresis Fresh Frozen Plasma (AFFP) is collected by apheresis using a ratio of 1 part sodium citrate anticoagulant to 16 parts whole blood or 1 part ACD-A anticoagulant to 11 parts whole blood and is frozen within 8 hours of collection. The component label clearly indicates the type and volume of anticoagulant in the component. AFFP contains both labile clotting factors V and VIII, plus all non-labile coagulation factors. Frozen Plasma (FP) is prepared from whole blood collected in approximately 70 mL of CPD anticoagulant, centrifuged and then separated from the red blood cells and buffy coat. The plasma is frozen within 24 hours of collection. FP is not labelled as leukoreduced as some units may contain ≥5x106 leukocytes/unit. FP contains all coagulation factors at levels similar to the levels in AFFP with the exception of the labile factors, V and VIII, which may be slightly reduced in FP. Cryosupernatant Plasma is prepared from slowly thawed FP that is centrifuged to separate the plasma from the insoluble cryoprecipitate. The insoluble cryoprecipitate is removed and the remaining plasma is refrozen. Cryoprecipitate is prepared from slowly thawed FP that is centrifuged to separate the insoluble cryopreciptate from the plasma. The insoluble cryoprecipitate is refrozen.