Intra-individual variability in troponin T concentration in dialysis patients

Results Thirty two of 61 patients had at least one result greater than the diagnostic cut-off for significant myocardial damage of 0.04 μg/L. The intra-individual variability was small; 99% of all the variance from each patient's median was ≤ 0.063 μg/L. Conclusions Intra-individual variability in TnT concentration is small enough to merit establishment a of baseline concentration for each haemodialysis patient. This baseline is stable over at least 15 weeks; samples need be collected no more frequently than this. A change in concentration of more than 0.06 μg/L from the individual's baseline is significant.