Workshop: Graph compression approaches in assembly
Computational Advances in Bio and Medical Sciences(2012)
摘要
Using a probabilistic data structure to store DNA assembly graphs results in a significant memory savings over other methods. As long as the Bloom filter remains below a specific false positive rate, it remains possible to traverse the graph. Using a Bloom filter has many applications in metagenomics, mRNAseq, read filtering, and error correction. We are currently exploring these possibilities and more.
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关键词
DNA,data structures,filtering theory,genomics,graph theory,molecular biophysics,probability,Bloom filter,DNA assembly graph,error correction,graph compression approach,mRNAseq,metagenomics,probabilistic data structure,read filtering,Bloom filters,de Bruijn graphs,k-mers,metagenomics,next-generation sequencing
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