Application of Optimal Control techniques and Advanced Computing to the study of enzyme kinetics
Mathematics and Computers in Simulation（2010）
Abstract
Abstract: In this paper we show some applications of Advanced and Parallel Computing to the study of mathematical models in Systems Biology and in particular of the network of biochemical reactions occurring inside a cell. Due to their high complexity, the numerical study of these systems must be approached by means of sophisticated Advanced Computing tools. In a deterministic framework, we show two examples of application of Optimal Control techniques to the study of the effects of a drug on enzyme reactions occurring inside a cell, where ''ad-hoc'' algorithms for the numerical solution of the Hamilton-Jacobi-Bellman equation are used in a parallel environment.
MoreTranslated text
Key words
numerical study,enzyme kinetics,michaelis–menten kinetics,sophisticated advanced computing tool,optimal control,parallel computing,biochemical reaction,hamilton–jacobi–bellman equations,systems biology,hamilton-jacobi-bellman equation,deterministic framework,optimal control technique,enzyme reaction,numerical solution,michaelis menten kinetics
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined