eMICAM a New Generation of Active DNA Chip with in Situ Electrochemical Detection
DESIGN, AUTOMATION AND TEST IN EUROPE CONFERENCE AND EXHIBITION, VOLS 1 AND 2, PROCEEDINGS（2005）
摘要
Most of the DNA chips available on the market are based on external or internal optical detection (fluorescence or chemiluminescence) and need a bulky chip reader (optics, laser, camera or PMT). We will present a new detection strategy using direct electrochemical detection of DNA hybridisation using conductive polymers grafted on an active silicon chip. We will report results on the first step of the fabrication process and emphasis on full wafer electropolymerisation of DNA probes on modified CMOS technology.
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关键词
situ electrochemical detection,dna probe,new generation,active dna chip,new detection strategy,active silicon chip,dna hybridisation,fabrication process,bulky chip reader,dna chip,direct electrochemical detection,conductive polymers,internal optical detection,cmos technology,fault tolerance,chip,silicon,yield,dna probes,fluorescence,cmos integrated circuits,dna,compression,conducting polymer
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