Zheng Yang - Department of Metabolism and Pharmacokinetics, The Bristol-Myers Squibb Pharmaceutical Research Institute

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Aconiti Lateralis Radix Praeparata Ameliorates Heart Failure Via PI3K/AKT/Bnip3 Pathway

Wenxiu Liu, Xingju Zou,Yang Zheng,Yuan Zhang, Guijuan Cui, Siyu Liu,Chen Sun,Cheng Peng

Frontiers in pharmacology (2025): 1526653-1526653

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Beyond MABEL: an Integrative Approach to First in Human Dose Selection of Immunomodulators by the Health and Environmental Sciences Institute (HESI) Immuno-Safety Technical Committee (ITC)

Mineo Matsumoto, Joseph Ryan Polli, Suresh K. Swaminathan,Kaushik Datta, Cris Kampershroer,Marie C. Fortin,Smita Salian-Mehta,Rutwij Dave,Zheng Yang, Payal Arora, Masanori Hiura, Mizuho Suzuki,Frank R. Brennan, Jean Sathish

CLINICAL PHARMACOLOGY & THERAPEUTICS（2024）

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Predicting Unpredictable Human Pharmacokinetics: Case Studies from the Trenches of Drug Discovery

Zheng Yang

Overcoming Obstacles in Drug Discovery and Developmentpp.317-349, (2023)

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Ado-tratuzumab Emtansine Beyond Breast Cancer: Therapeutic Role of Targeting Other HER2-positive Cancers

Yang Zheng, Jiayu Zou,Chen Sun,Fu Peng,Cheng Peng

FRONTIERS IN MOLECULAR BIOSCIENCES（2023）

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Repression of Organic Anion Transporting Polypeptide (OATP) 1B Expression and Increase of Plasma Coproporphyrin Level As Evidence for OATP1B Downregulation in Cynomolgus Monkeys Treated with Chenodeoxycholic Acid

Yueping Zhang,Shen-Jue Chen,Cliff Chen,Xue-Qing Chen,Sagnik Chatterjee,David J. Shuster, Heather Dexter,Laura Armstrong, Elizabeth M. Joshi,Zheng Yang,Hong Shen

DRUG METABOLISM AND DISPOSITIONno. 8 (2022): 1077-1086

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Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein

Zheng Yang,James Loy,Brian Poirson,Yanshan Dai,Surendran Rajendran,Shihua Xu,Vanessa Spires,Murali Gururajan,Zheng Lin,Jaren Arbanas,Stephen Carl,Samantha Pace,Yun Wang,John Mehl,Krishna Vasudevan, Thomas Spires, Ruslan Novosiadly, Shodeinde Coker, Raymond Perez, Kelly Covello,Paul Morin,Robert Graziano,Miranda Broz,Lois Lehman-McKeeman

Frontiers in Pharmacology（2022）

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Prospective Prediction of Plasma Pharmacokinetics of a Novel Immune-Modulating Agent in Cancer Patients after Intra-Tumoral Administration: Translation from Non-Clinical Species to Humans

Ragini Vuppugalla,Ramola Sane,Michael Wichroski, Ashvini Kumar Gavai, Sarandeep Boyanapalli,Zheng Yang

Xenobiotica（2021）

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Achieving a Low Human Dose for Targeted Covalent Drugs: Pharmacokinetic and Pharmacodynamic Considerations on Target Characteristics and Drug Attributes

Zheng Yang

BIOPHARMACEUTICS & DRUG DISPOSITION（2021）

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