基本信息
views: 190
Career Trajectory
Bio
自我简介
My research focuses on data analysis of cancer genomic data. I am a trained bioinformatician with more than 10 years of experience. Since 2011 I joined MD Anderson and have been extensively involved in The Cancer Genome Atlas project. In addition to contributing to the TCGA Glioblastoma and lower grade glioma analyses, I analyzed genomic instability by examining DNA breakpoints in GBM. I performed a longitudinal analysis of GBM recurrence, in which I extensively investigated the clonal architecture of GBM. Since 2013 I have worked on the TCGA adrenocortical carcinoma (ACC) project as data and analysis coordinator. This project involves a comprehensive analysis of ACC molecular data generated by our consortium. My research comprehends data including DNA/RNA sequencing, copy number and methylation. I programed the RNA sequencing pipeline PRADA (http://bioinformatics.mdanderson.org/main/PRADA:Overview). A highlight of the tool is the high sensitivity and specificity of gene fusion detection.
My long time research interest is to understand genomic instability in cancer initiation and progression, and how to use the information to predict prognosis, clinical response to therapy, etc.
A full list of publications at PubMed
http://www.ncbi.nlm.nih.gov/sites/myncbi/1lQwkc6atlSkr/bibliography/48172182/public/?sort=date&direction=descending
Follow me on Twitter:
https://twitter.com/zhengsiyuan
Research Interests
Papers共 199 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Debodipta Das, Xiaojing Wang,Yu-Chiao Chiu,Hakim Bouamar,Francis E Sharkey,Jorge E Lopera,Zhao Lai,Susan T Weintraub,Xianlin Han,Yi Zou, Hung-I H Chen, Carla R Zeballos Torrez,
medRxiv : the preprint server for health sciences (2024)
Yi Xu,Michael H. Nipper, Angel A. Dominguez,Zhenqing Ye,Naoki Akanuma,Kevin Lopez,Janice J. Deng, Destiny Arenas, Ava Sanchez,Francis E. Sharkey,Colin M. Court,Aatur D. Singhi,
crossref(2023)
Pooja Yadav,Panneerdoss Subbarayalu, Daisy Medina, Saif Nirzhor,Santosh Timilsina,Subapriya Rajamanickam, Vijay K. Eedunuri,Yogesh Gupta,Siyuan Zheng,Nourhan Abdelfattah,Yufei Huang, Ratna Vadlamudi,
crossref(2023)
Liem M. Phan,Enrique Fuentes-Mattei,Weixin Wu,Guermarie Velazquez-Torres, Kanishka Sircar, Christopher G. Wood,Tao Hai,Camilo Jimenez,Gilbert J. Cote,Levent Ozsari,Marie-Claude Hofmann,Siyuan Zheng,
crossref(2023)
Fenghua He,Abhik Bandyopadhyay,Laura J. Klesse,Anna Rogojina,Erin Butler, Taylor Hartshorne, Trevor Holland,Luz Perez Prado, Anne-Marie Langevan,Allison Grimes,Chatchawin Assanasen,Zhao Lai,
Cancer Researchno. 7_Supplement (2023): 3572-3572
crossref(2023)
Funan He,Abhik M Bandyopadhyay,Laura J Klesse,Anna Rogojina,Sang H Chun,Erin Butler,Taylor Hartshorne, Trevor Holland,Dawn Garcia,Korri Weldon, Luz-Nereida Perez Prado,Anne-Marie Langevin,
Nature communicationsno. 1 (2023): 7600-7600
crossref(2023)
Xiaolong Li,Emmanuel Martinez-Ledesma,Chen Zhang,Feng Gao,Siyuan Zheng, Jie Ding,Shaofang Wu,Nghi Nguyen,Stephan C. Clifford,Patrick Y. Wen,Keith L. Ligon, W.K. Alfred Yung,
crossref(2023)
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn