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个人简介
Dr. He is a basic science researcher by training in the fields of biochemistry and molecular biology and has been conducting clinical research for the past 20 years at Nemours. She advocates bench to bed research approaches that can directly improve care to patients and has strong collaboration with Nemours clinicians, from GI, ENT, and Pulmonary to Anesthesiology. Dr. He plays a key role in mentoring and supporting GI fellow research from study design, funding, and data analysis to final manuscript writing.
Her current research focuses on GI diseases such as celiac disease, IBD, intestinal dysfunction and pancreatic deficiency, and extra-esophageal reflux. Dr. He’s lab developed a sensitive biomarker to detect extra-esophageal reflux (EER) in children with upper airway diseases. Currently, Nemours is the only laboratory that provides this as a diagnostic test to assess the effects of extra-esophageal reflux on airway conditions. Dr. He and her collaborators are well recognized for their contribution in this field. They have published several key papers and collaborated with investigators nationally and internationally. Their research results and certified clinical test for EER biomarker led to clinical trials funded by pharmaceutical companies and invitations to international meetings. In the past several years, they were awarded with grants from NIH and other institutional funding and contract research.
Under Dr. He’s leadership, Nemours’ GI clinical lab continuously grows in test volume and new test additions via implementation of robotic instrumentation and data management automation. The GI lab is completely financially independent, with annual revenue over one million in recent years, which has been a major financial resource to GI fellow research. The GI clinical lab offers five complex diagnostic assays nationwide to evaluate diseases such as intestinal and pancreatic dysfunctions, IBD, celiac diseases and EER. Dr. He’s long-term goal is to continue research, particularly to identify new and better biomarkers for GI and other diseases, establish reference guidelines based on age, disease progression and disease phenotypes, and derive new research directions from large and standardized clinical data. The goal is to provide precise scientific evidence to monitor disease progress and guide intervention.
研究兴趣
论文共 65 篇作者统计合作学者相似作者
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Kesavan Sadacharam,Zhaoping He, Maureen F. Edelson, Kimberly McMahon, Catherine Madurski,B. Randall Brenn
North American Spine Society Journal (NASSJ) (2022): 100135-100135
Jennifer Ezirike Ladipo,Zhaoping He,Kudakwashe Chikwava, Katherine Robbins,Jonathan Beri,Zarela Molle-Rios
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITIONno. 3 (2021): 352-357
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