基本信息
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Bio
Our laboratory is primarily focusing on developing and applying solution-state NMR methods, together with computational and biochemical approaches, to understand the molecular basis of RNA function. In particular, we aim to visualize, with atomic resolution, the entire dynamic process of ribozyme catalysis, riboswitch-based gene regulation, and co-transcriptional folding of mRNA. The principles deduced from these studies will provide atomic basis for rationally manipulating RNA catalysis and folding, and for de novo design of small molecules that target specific RNA signals involving in cancer and human disease. Research program in the laboratory provides diverse training opportunities in areas of spectroscopy, biophysics, structural biology, computational modeling, and biochemistry.
Research Interests
Papers共 49 篇Author StatisticsCo-AuthorSimilar Experts
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Nucleic acids researchno. 13 (2024): 7971-7986
Rhese D Thompson,Derek L Carbaugh,Joshua R Nielsen, Ciara M Witt,Rita M Meganck,Atul Rangadurai,Bo Zhao,Jeffrey P Bonin,Nathan I Nicely,William F Marzluff,Aaron T Frank,Helen M Lazear,
Research square (2023)
Min-Guk Cho,Rashmi J. Kumar, Chien-Chu Lin,Joshua A. Boyer,Jamshaid A. Shahir,Katerina Fagan-Solis,Dennis A. Simpson,Cheng Fan, Christine E. Foster, Anna M. Goddard,Qinhong Wang,Ying Wang,
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2020)
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Author Statistics
#Papers: 49
#Citation: 2648
H-Index: 25
G-Index: 49
Sociability: 5
Diversity: 1
Activity: 0
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