Prof. Dr. Jiwen Zhang, now serves as the principal investigator in Shanghai institute of Materia Medica (SIMM), Chinese Academy of Science. He has carried out the interdisciplinary research by establishing cooperation with research team at home and abroad. Aiming at the evaluation of DDS, he has established the pharmacokinetics theory for the sustained and controlled-release systems, putting forward the quantitative method for optimizing the formulation of the sustained and controlled-release systems, and has designed new formulation such as biomimetic DDS. Pointing at the complexity of the structure of pharmaceutical dosage forms, his team utilized primarily the synchrotron radiation light facility to establish quantitative methods for characterizing the irregular and dynamic structure of DDS. Novel cage-like tablet and the osmotic pump with new structures have been designed. His team has studied the release mechanisms associated with kinetic rate constants of supramolecular DDS by HPLC, SPR and SPRi as well as prediction by molecular simulation. He and his team are working on Structure Pharmaceutics for scales from molecule to dosage forms.