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Dr. Yau has focused her research on the epidemiology, diagnosis and management of multi-drug resistant bacterial pathogens in cystic fibrosis (CF). Her research involve examining the epidemiology and clinical significance of Stenotrophomonas maltophilia infections in pediatric and adult CF patients, as well as determining the most effect antimicrobial combinations for the treatment of this infection in CF. She was the co-principal investigator on a multi-center randomized controlled trial evaluating the utility of biofilm susceptibility assay in choosing more effective antibiotics to treat CF patients with chronic Pseudomonas aeruginosa pulmonary infection. She is also involved in a national multicentre study to determine the role of transmissible, clonal P. aeruginosa in the Canadian CF patient population and part of a CIHR-funded Canadian Microbiome initiative characterizing the polymicrobial communities in the CF lung. In addition, Dr. Yau is investigating the use of novel antimicrobial agents/modalities in the treatment of CF patients with multi-drug resistant Gram negative bacterial pulmonary infections and studying the role bacterial interactions on the formation of biofilm by Pseudomonas aeruginosa in CF patients.
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论文共 75 篇作者统计合作学者相似作者
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AMERICAN JOURNAL OF CLINICAL NUTRITIONno. 2 (2024): 485-495
NEUROIMAGE-CLINICAL (2023): 103523-103523
biorxiv(2022)
bioRxiv (Cold Spring Harbor Laboratory) (2022)
Ramzi Fattouh,Patrick J. Stapleton,AliReza Eshaghi, Angela D. Thomas,Michelle E. Science,Tal Schechter, Laurie Streitenberger,Petr Hubacek,Yvonne C. W. Yau,Martha Brown,Morag R. Graham,Jonathan B. Gubbay,
Amanda J. Morris,Lindsay Jackson,Yvonne CW Yau,Courtney Reichhardt,Trevor Beaudoin, Stephanie Uwumarenogie, Kevin M. Guttman,P. Lynne Howell,Matthew R. Parsek,Lucas R. Hoffman,Dao Nguyen,Antonio DiGiandomenico,
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