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The increasing prevalence of overweight and obesity is a major public health concern in these days. Recently, growing evidence indicate that the obese population are more susceptible to some neurological conditions such as cognitive disorders, including Alzheimer’s disease (AD) or mood disorders, including major depression disorder (MDD). These evidences indicate that changes in the organism that accompany overweight and obesity can ultimately lead to CNS dysfunction. However, the pathophysiological mechanisms and molecular players underlying this connection are poorly known. In this study, I focus on the mechanistic correlation between obesity and neurological disorders (such as Alzheimer’s disease or Depression). To address this correlation, I approach using multidisciplinary way from gene to behavior level. Using this systematic exploration of this relationship would help to elucidate causal mechanism and opportunities for prevention and treatment.
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International journal of molecular sciencesno. 20 (2023): 15064-15064
Neuronno. 4 (2023): 611-627.e8
Moonseok Choi,Junghwa Ryu,Huy Duc Vu,Dongsoo Kim,Young-Jin Youn, Min Hui Park,Phuong Tu Huynh, Gyu-Bin Hwang,Sung Won Youn,Yun Ha Jeong,Bruno Imbimbo
International journal of molecular sciencesno. 19 (2023): 14954-14954
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