张媛 - College of Life Sciences, Shaanxi Normal University

基本信息

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职业迁徙

个人简介

张媛，博士，教授，博士生导师。2011年在陕西师范大学获得博士学位，2013-2016年在美国Thomas Jefferson University神经科学系做博士后研究。2011年至今在陕西师范大学药用资源与天然药物化学教育部重点实验室从事教学科研工作。

主要从事中枢神经系统脱髓鞘疾病的发病机制、药物靶点及分子药理的研究工作，先后主持国家自然科学基金2项、科技部项目1项、陕西省自然科学基金3项、陕西省高校科协青年人才托举计划项目1项、中央高校科研项目3项，作为主要完成人参与美国NIH R01项目2项。已发表科研论文60余篇，以第一或通讯作者在本领域国际顶级期刊PNAS、Molecular Therapy、Metabolic Engineering、Brain, Behavior, and Immunity、Frontiers in Immunology等发表研究论文26篇（其中SCI I区论文9篇、II区9篇）。申请专利9项，授权1项。2018年入选陕西省青年科技新星。

主要研究领域及兴趣

1. 髓鞘再生的分子机制

2. 中枢神经系统脱髓鞘疾病的药物筛选

研究兴趣

论文共 215 篇作者统计合作学者相似作者

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

Engineered Extracellular Vesicles for TGF-β Encapsulation As a Therapeutic Strategy Against LPS-induced Systemic Inflammation

Zhuo-Hua Zhao,Bo Huang, Zi-Han Fang,Wen-Hui Qi,Jin He,Li-Bin Wang,Yuan Zhang,Xing Li

INTERNATIONAL IMMUNOPHARMACOLOGY (2025)

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Methamphetamine Inhibits Huntingtin-Associated Protein 1-Mediated Tyrosine Receptor Kinase B Endocytosis Resulting the Neuroprotective Dysfunction of Brain-Derived Neurotrophic Factor

Baoyu Shen, Zhenling Wu, Mengran Lv,Genmeng Yang, Yuanyuan Cao,Yuan Zhang, Junjie Shu, Wenjuan Dong, Zhenping Hou, Di Jing, Xinjie Zhang, Yuhan Hou, Jing Xu,Shijun Hong,Lihua Li

TOXICOLOGY (2025)

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A Bibliometric Analysis of Research on the Mitochondrial Roles in Prostate Cancer and the Virtual Design of LONP1 - Specific Antibodies Using the GeoBiologics Platform

jiawei PAN,Yuan ZHANG, Linglong JIANG, Yuwei SHEN, Yangyang SUN,Jundong ZHU,CHEN Zhen,Min FAN, Jian SHI

biorxiv（2025）

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[Phenotypic and Pathogenic Variant Analysis of an X-linked Dominant Inherited Non-Syndromic Hearing Loss Pedigree]

Ziyu Zhai, Hongen Xu,Le Wang,Xiaodan Zhu,Yuan Zhang, Ling Li, Xiaosai Zhang,Tingxian Li, Kaixi Wang,Fanglei Ye

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgeryno. 6 (2025): 570-573;577

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Baicalin Ameliorates Neuroinflammation by Targeting TLR4/MD2 Complex on Microglia Via PI3K/AKT/NF-κB Signaling Pathway

Yufang Lu, Ruiying Zhou, Ruyi Zhu, Xue Wu, Jin Liu, Yue Ma,Xin Zhang, Yaling Zhang,Luting Yang, Yanhua Li,Yuan Zhang,Yaping Yan,Qian Zhang

Neuropharmacologypp.110296, (2025)

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Multifunctional Injectable Hydrogel with Self-Supplied H2S Release and Bacterial Inhibition for the Wound Healing with Enhanced Macrophages Polarization Via Interfering with PI3K/Akt Pathway

Liyang Gong, Le Chang,Siyu Chen, Xuan Wei, Huiping Du, Jiamin Cheng, Xiaoxuan Chen,Zhang Yuan,Pan Zhao,Meijuan Geng,Hui Yang,Kaiyong Cai,Liangliang Dai

Biomaterialspp.123144, (2025)

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Nuclear Receptor PPARγ Targets GPNMB to Promote Oligodendrocyte Development and Remyelination

Bing Han, Ming-Yue Bao, Qing-Qing Sun, Rui-Ning Wang, Xin Deng,Kun Xing, Feng-Lin Yu,Yan Zhang, Yue-Bo Li, Xiu-Qing Li, Na-Nan Chai, Gai-Xin Ma, Ya-Na Yang, Meng-Yuan Tian, Qian Zhang,Xing Li,Yuan Zhang

BRAIN（2025）

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TIA1-Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Through Upregulating IL-31RA Signaling