He has been working on inventing real-time, in-situ bio-aerosol detection and characterization systems for years, mainly based on single particle fluorescence spectra, two-dimensional angular optical scattering patterns, and Raman spectroscopy. Some of the advancements have been transitioned to DARPA, DTRA, DHS, USAMIID, ARL, ITT, and SNL. He has over 80 refereed journal papers, 3 book chapters, and 6 patents, over 1900 citations. He has successfully completed more than 20 research projects supported by DARPA, DTRA, JBTDS, DHS, ARO, AFOSR, DOE as a principal investigator (PI), Co-PI, or key personnel.