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长期从事肿瘤相关蛋白复合物的结构与功能研究、抗癌药物新靶标的发现、以及蛋白结构基础上的抗癌药物研发。至今已发表 SCI 论文 100 多篇,其中以通讯/第一作者在Nature Communications、Nucleic Acids Research、Journal of the American Chemical Society、Signal Transduction and Targeted Therapy 、Journal of Hematology and Oncology、Journal of Medicinal Chemistry等杂志发表论文70多篇(14篇IF>15),4篇获选“ESI高被引论文”。与国内外多个实验室展开密切合作,以蛋白结构为基础,设计研发了一系列小分子靶向新药,已在体内外肿瘤模型中取得显著抑瘤效果。承担国家自然科学基金项目、湖南省重点科研项目10余项,入选湖南省科技创新领军人才、湖南省“百人计划”、湖南省高层次卫生人才“225”工程、湖湘高层次人才聚集工程、中南大学“升华学者”,获湖南省科技进步二等奖1项,获湖南医学科技奖一等奖各1项。申请中国及国际发明专利10多项,已授权6项。主编专著1部。
Research Interests
Papers共 187 篇Author StatisticsCo-AuthorSimilar Experts
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iScienceno. 4 (2024): 109377-109377
Fang Yang,Qianmeng Lin,Xiaojuan Song,Huisi Huang,Xiaojuan Chen, Jianwen Tan,Yun Li, Yang Zhou,Zhengchao Tu,Hongli Du, Zhi-min Zhang,Raquel Ortega,
JOURNAL OF MEDICINAL CHEMISTRYno. 4 (2024): 2667-2689
Shuyan Dai,Liang Guo,Raja Dey,Ming Guo, Xiangqian Zhang,Darren Bates, Justin Cayford,Longying Jiang,Hudie Wei,Zhuchu Chen,Ye Zhang,Lin Chen,
Structureno. 4 (2024): 467-475.e3
Cell Death & Diseaseno. 1 (2024): 1-15
Cell Death & Diseaseno. 3 (2024): 1-13
Cell death and differentiationpp.1-13, (2024)
Interdisciplinary Sciences: Computational Life Sciencesno. 2 (2024): 1-15
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116281-116281
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Author Statistics
#Papers: 185
#Citation: 4510
H-Index: 34
G-Index: 34
Sociability: 6
Diversity: 4
Activity: 324
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