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个人简介
Throughout my scientific career, I focused my interest and research on the adaptive immune system. I studied the T cell development at the human thymus during my PhD (1996-2001, CBMSO, Madrid), with several scientific contributions to the field. In my postdoctoral period (2002-2007, LRI-CRUK, London), I worked in B cells and the activation events that lead to the humoral immune response. My scientific contributions from that period contributed to the B cell field revolution of the last decade. At the stage of Principal Investigator (from 2007-to-date, at the CNB-CSIC, Madrid), I focused my attention in the behavior plasticity that B cells showed in vivo. My research pursues to understand the molecular mechanisms that regulate B cell behavior (motility, immune synapse) in response to distinct external stimuli (antigen, inflammation, …), and how changes in cell dynamics shape the B cell ability to respond. Also, how cell behavior alteration drives B cell-related pathologies (primary immunodeficiency, leukemias/lymphomas).
研究兴趣
论文共 67 篇作者统计合作学者相似作者
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Eva M. García-Cuesta,Pablo Martínez,Karthik Selvaraju, Gabriel Ulltjärn, Adrián Miguel Gómez Pozo,Gianluca D’Agostino,Sofía Gardeta,Adriana Quijada-Freire, Patricia Blanco Gabella,Carlos Roca, Daniel del Hoyo,Rodrigo Jiménez-Saiz,
biorxiv(2024)
Nieves Fernández-Gallego,Raquel Castillo-González, Lucía Moreno-Serna, Antonio J. García-Cívico,Elisa Sánchez-Martínez,Celia López-Sanz,Ana Luiza Fontes,Lígia L. Pimentel,Ana Gradillas,David Obeso, René Neuhaus,Marta Ramírez-Huesca,
Allergy (2024)
Immunology Letters (2023): 68-72
Science Advancesno. 3 (2022)
Silvia Sevilla-Movilla,Patricia Fuentes, Yaiza Rodríguez-García,Nohemi Arellano-Sánchez,Peter W Krenn, Soledad Isern de Val,Sara Montero-Herradón,Javier García-Ceca, Valeria Burdiel-Herencia,Sofía R Gardeta,Noemí Aguilera-Montilla,Celia Barrio-Alonso,
Biophysical journalno. 9 (2021): 1692-1704
Sara Rodríguez,Cirino Botta,Jon Celay,Ibai Goicoechea,Cristina Jiménez,Maria J Garcia-Barchino, Rafael Valdés-Mas,Yolanda Carrasco,Juan José Garcés,Marta Larrayoz, Susana Santos,Diego Alignani,
Blood (2020): 42-43
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