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Bio
Professor Yin is one of the leading scientists in the field of redox regulation of glucose and lipid metabolism in human metabolic diseases. His research interest has been focusing on the understanding of metabolic reprogramming in carbohydrate and lipid metabolism in metabolic diseases including atherosclerosis, liver cancer, hyperuricemia and gout. For the past 20 years, Prof. Yin has made significant contributions in understanding the roles and underlying mechanisms of free radical lipid peroxidation in human diseases including atherosclerosis using the state-of-the art metabolomics/lipidomics approaches (Yin et al JACS, 2000; 2002; Yin et al Chem. Rev. 2011; Zhong et al, Redox Biol. 2015; Zhong et al, Free Radic. Biol. Med. 2019), and discovered the novel non-enzymatic functions of Aldehyde Dehydrogenase 2 (ALDH2) in cardiovascular disease (CVD) (Zhong et al, J. Clin. Invest. 2019; Li et al, JCI Insight, 2021; Zhong et al, Redox Biol. 2021; Zhang et al, Nat. Rev. Cardiol. 2023). His research for the past five years has defined the pathways in metabolic reprogramming in liver cancer mediated by a key glycolytic enzyme fructose-1,6-bisphosphate aldolase B (ALDOB) (Li et al, Nature Cancer, 2020; He et al, PLoS Biol., 2020; Liu et al, Hepatology, 2021). Using a precision medicine approach based on metabolomics and machine learning algorithms, Prof. Yin and his collaborators have established prediction models in assessing risks for gout attacks in asymptomatic hyperuricemia patients and the frequencies for gout flares (Shen et al, Arthritis. Rheumatol., 2021; Lu et al, Nat. Rev. Rheumatol., 2019). Since 2000, Prof. Yin has co-authored around 160 peer-reviewed manuscripts in SCI-indexed journals including Science, Nature, Cell Metabolism, Nature Cancer, Nature Metabolism, Nature Review Cardiology, Nature Reviews Rheumatology, Molecular Cell, Journal of American Chemical Society, Hepatology, Redox Biology, Arthritis & Rheumatology, Free Radical Biology and Medicine, Journal of Biological Chemistry, Journal of Clinical Endocrinology and Metabolism, and Journal of American Society for Mass Spectrometry with >11,400 Google Scholar citations and h-index of 58 (as of February 2023). Prof. Yin has been listed as the top 2% of the Most-Cited Scientists by Stanford University since 2021 and was awarded prestigious “Senior International Scientists” in 2021 by National Natural Science Fund of China.
Research Interests
Papers共 213 篇Author StatisticsCo-AuthorSimilar Experts
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASEno. 3 (2024): 167009-167009
Yaxu Li, Qiao Ran, Qiuhui Duan,Jiali Jin,Yanjin Wang,Lei Yu, Chaojie Wang,Zhenyun Zhu,Xin Chen,Linjun Weng,Zan Li,Jia Wang,
Natureno. 7998 (2024): 411-418
MOLECULAR NUTRITION & FOOD RESEARCHno. 2 (2024): e2300115-e2300115
Xia Shen,Shuyuan Guo,Ningning Liang,Mingming Zhao, Chun Wang, Zi Li, Dewen Yan,Lemin Zheng,Huiyong Yin
Clinical and translational medicineno. 6 (2024): e1722-e1722
Frontiers in endocrinology (2023): 1138984
Gout, Urate, and Crystal Deposition Diseaseno. 1 (2023): 49-61
Chunzhao Yin,Cunzhen Zhang,Yongqiang Wang,Guijun Liu,Ningning Wang,Ningning Liang,Lili Zhang,Qiaochu Tu,Jingwen Lv,Huimin Jiang, Haoran Ma, Chenxi Du,
Hepatology (Baltimore, Md.) (2023)
Nature reviews. Cardiologyno. 7 (2023): 495-509
Circulationno. 19 (2023): 1467-1470
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Author Statistics
#Papers: 215
#Citation: 11596
H-Index: 57
G-Index: 104
Sociability: 7
Diversity: 0
Activity: 2
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