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聚焦蛋白质的O-糖基化研究,揭示蛋白质精准修饰调控机制和生物学意义,在糖基转移酶的功能发现,胞内蛋白质新型糖基化发现,疾病糖链异质体生物标志物的发现,人源糖蛋白生物合成等方面取得系列成果。张延课题组的蛋白质精准糖基化研究在国内具有独特的学科特色,揭示了与肿瘤、发育密切相关蛋白质O-糖基化修饰的精准调控机制和意义;在结直肠癌,肺癌,肝纤维化,阿尔兹海默症等疾病中研究发现基于糖链的生物标志物。
Research Interests
Papers共 217 篇Author StatisticsCo-AuthorSimilar Experts
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Wangrui Lei,Xuezeng Xu, Ning Li,Yan Zhang,Ran Tang,Xiaoru Li,Jiayou Tang,Xue Wu,Chenxi Lu,Yajun Bai, Yu Yao,Zhenye Qiu,
Biochemical pharmacology (2024): 116035-116035
Yao Yao, Mei Yuan, Min Shi, Wenyu Li, Yuqian Sha,Yan Zhang, Canli Yuan,Jianping Luo,Zhenyu Li, Chengcheng Liao,Kailin Xu,Mingshan Niu
Blood Advancesno. 15 (2024): 4003-4016
Yanfei Zhao,Yan Zhang, Yude Huang, Yiyang Fan, Lixiang Zhao, Linjing Gao, Dongqin Mo, Xian Wang,Daiyou Wang
JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCESno. 2 (2024): 100872
Xiao Cheng,Chunyu Yu,Yan Zhang,Yani Peng, Yuncheng Liu, Hangwei Fa,Lu Xia, Leyi Qin,Sudun Guan, Xiaodi Wu,Jiajing Wu,Yue Wang,
iSciencepp.110276, (2024)
Di Yin,Yiye Zhong,Sikai Ling, Sicong Lu,Xiaoyuan Wang, Zhuofan Jiang,Jie Wang,Yao Dai,Xiaolong Tian, Qijing Huang,Xingbo Wang,Junsong Chen,
Nature biomedical engineeringpp.1-16, (2024)
Clinical Immunology (2024): 109861-109861
WORLD JOURNAL OF HEPATOLOGYno. 5 (2024): 809-821
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Author Statistics
#Papers: 224
#Citation: 9048
H-Index: 46
G-Index: 93
Sociability: 7
Diversity: 4
Activity: 198
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