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个人简介
Our laboratory focuses on cancer and viral chemotherapy. We are studying the functional roles and properties of virus-specific proteins in order to design selective antiviral compounds. Some anti-HIV drugs have selective action against mitochondrial DNA synthesis that could lead to toxicity. This observation offered the opportunity to develop new antiviral drugs without such side effects and to examine the role of mitochondrial DNA synthesis in nuclear DNA synthesis. A new class of biological active nucleoside analogs, L(-)nucleosides were discovered. Drug resistance is a critical issue in cancer chemotherapy.
研究兴趣
论文共 786 篇作者统计合作学者相似作者
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Michelle I. Lin,Jun Yu, Erik D. Weiss, Zao Li Jiang, Todd A. Fairchild,Yasuko Iwakiri,Roberto Groszmann, Kevin P. Claffey,Yung-Chi Cheng,William C. Sessa
CANCER CELLno. 6 (2024): 1127-1127
Nipun Verma,Kimberly L Johung,Jeremy Kortmansky, Wajih Zaheer,Jill Lacy,Michael Cecchini,Stacey Stein,Yung-Chi Cheng,Wing Lam,Shwu-Huey Liu,Vikram Reddy,Howard Hochster,
Journal of gastrointestinal oncologyno. 3 (2024): 1050-1059
Hsiao-Lan Chen,Chia-Hung Chen,Wen-Che Hsieh, Yu-Han Huang,Tzu-Ju Hsu,Fuu-Jen Tsai,Yung-Chi Cheng,Chao-Yu Hsu
Scientific reportsno. 1 (2024): 14330-14330
Acupuncture and Herbal Medicine (2024)
Cancer cellno. 6 (2024): 1127-1127
CANCER RESEARCHno. 7 (2023): 3078-3078
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作者统计
#Papers: 780
#Citation: 52880
H-Index: 97
G-Index: 207
Sociability: 8
Diversity: 1
Activity: 1
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