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从事成体干细胞体内调控及皮肤干细胞用于组织工程皮肤及附属器官再生的研究。建立了完整的皮肤干细胞分离、培养和鉴定体系,以及皮肤再生修复和毛囊再生动物模型,在毛囊和皮脂腺再生领域取得了一定的进展。发现了损伤可以诱导毛囊再生的现象,证明了巨噬细胞-TNF-a在损伤诱导的毛囊再生中的核心作用。相关研究成果发表在Nature Communications (Wang, Chen et al. 2017)中,该论文为国内毛囊再生研究领域中首篇Nature系列文章。同时还建立了新型的伤口愈合分析模型及利用干细胞促进伤口愈合的方法,相关研究成果发表在Nature Protocols (Wang, Ge et al. 2013),该文章是国内伤口愈合领域的首篇Nature系列文章,该研究获得2016年深圳市科学技术奖。以第一作者在Nature Communications,Nature Protocols等杂志发表论文5篇(包括著作1篇)。共申请专利6项,包括PCT专利1项。近期的研究中,建立双CRE多种干细胞体内追体系,可以实现两种干细胞的体内独立敲除和追踪。该体系将对干细胞体内重编程及干细胞与肿瘤干细胞之间相互转化的研究有重要研究意义。获得国家青年基金,中国博士后特别资助,中国博士后基金面上项目等基金的资助。
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Papers共 40 篇Author StatisticsCo-AuthorSimilar Experts
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European Journal of Dermatologyno. 6 (2024): 710-712
Miaomiao Li,Xusheng Wang, Rosalind Kieran, Zheng Wei Sun,Yubin Gong,Hongzhao Lei,Bin Sun,Li Xiao,Yanlin Wang, Song Wang,Zhiyu Li,Luying Wang,
Frontiers in oncology (2024): 1336763-1336763
Yujie Xu,Yuyang Gan, Fangfang Qi, Xinyu Lu, Xiaofei Zhang,Jiarui Zhang,Hailin Wang,Yue Li, Zhiyang Zhou,Xusheng Wang,Dongqiang Zeng, Feng Lu,
Acta Biomaterialia (2024): 296-312
Yumiao Lin, Xinxin Li,Jingxian Fang, Qinglan Zeng,Danling Cheng,Gaofeng Wang, Runlu Shi,Yilin Luo, Yihe Ma,Miaomiao Li,Xiang Tang,Xusheng Wang,
Biochemical and biophysical research communications (2023): 9-19
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2023): 1-6
Xinxin Li, Runlu Shi,Lingchen Yan,Weiwei Chu,Ruishuang Sun, Binkai Zheng, Shuai Wang,Hui Tan,Xusheng Wang,Ying Gao
Natural products and bioprospectingno. 1 (2023): 1-16
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#Papers: 40
#Citation: 2542
H-Index: 17
G-Index: 27
Sociability: 5
Diversity: 3
Activity: 63
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