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职业迁徙
个人简介
I have a broad background in neuroscience and pharmacology, with specific training and expertise in behavioral, neurochemical and neurobiological analyses in animal models related to neuropsychiatric disorders, such as depression, anxiety and neuropathic pain. My research includes investigation of CNS functional roles of natural polyphenols (curcumin, resveratrol and ferulic acid) and the selective phosphodiesterases (PDEs) inhibitors (PDE2, 4 and 5) for treatment of stress-related neuropsychiatric and neurodegenerative disorders, in the mediation of the above diseases and the involved intracellular mechanisms. As PI or co-Investigator on the institutional- and NIH funded grants, I laid the groundwork for the proposed research by assessing the roles of PDE in stress-induced depression, anxiety and memory impairment in aspects of behavior and molecular biology. Recently, my project focused on investigating the predictive factors relevant to stress-induced depression and neuropathic pain, as well as the signal pathway.
研究兴趣
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